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Zhang Hua

2024-11-14 21:23:32

Curriculum Vitae

I. Personal information

Hua Zhang, Ph.D, associate Professor, doctoral supervisor.

National Licensed Veterinary Practitioner, mentor of the Pet Doctor Specialized Class. Concurrently serves as a council member of the Veterinary Surgery Branch of the Chinese Veterinary Medical Association, a member of the Clinical Veterinary Expert Database of the China Animal Disease Prevention and Control Center, an expert reviewer for the national random check of academic theses, and a science and technology commissioner of Pinggu District, Beijing. Serves as a reviewer for authoritative journals such as Carbohydrate Polymers, International Journal of Biological Macromolecules, Chinese Journal of Animal Science and Veterinary Medicine, Acta Veterinaria Sinica, and Chinese Journal of Animal Nutrition.

II. Research interests

Mainly engaged in research on animal clinical disease diagnosis and prevention, the mechanism and application of natural bioactive substances, as well as the development and evaluation of new drug formulations.

III. Research Projects

1. National Natural Science Foundation of China - General Project, Research on the Regulatory Effect and Mechanism of Silybin-Chitosan Nanoparticles on Liver Ischemia-Reperfusion Injury in Dogs, Principal Investigator (2024 - 2027);

2. National Natural Science Foundation of China - Young Scientist Fund Project, The Role and Molecular Mechanism of Shell Oligosaccharides in Immunosuppression and Inflammatory Response Caused by Surgical Trauma in Dogs, Principal Investigator (2018 - 2020);

3. University Young Teachers' Research Fund Project, Preliminary Application of Shell Oligosaccharides in the Repair of Abdominal Lymph Node Partial Resection Injury in Dogs, New Rui Peng Medical Group, Principal Investigator (2021 - 2022);

4. Enterprise Horizontal Cooperation Project, Development and Verification of New Functional Feed Additives, Jiangsu Aomei Biotechnology Co., Ltd., Principal Investigator (2021 - 2022);

5. Beijing Education Commission Science and Technology Project, Screening of Anti-S. aureus Biofilm Chinese Medicines and Research on Their Combined Application with Chitosan, Beijing Education Commission, Principal Investigator (2017 - 2019).

IV. Major Achievements

(Ⅰ) Major prize-winning achievements

1. Integration and Promotion of Key Technologies for Healthy Milk Cow Production, Beijing Agricultural Extension Award, Third Prize, Beijing Municipal Government, September 2019

2. Investigation on the Current Situation of Preventing Zoonotic Diseases among Community Residents in Beijing, Excellent Project of Social Research by Young Teachers of Beijing Universities, Second Prize, Communist Party Committee of Beijing Education Commission, December 2016

(Ⅱ) Representative papers

1. Kaiming Wang, Yumeng Gao, Zhenlin Jiang, Jinjin Tong, Hua Zhang. Chitosan nanoparticle delivery enhances the antibacterial performance and bioactivity of bovine lactoferricin against staphylococcus aureus-associated mastitis. J Agric Food Chem,2026,74(1):1422-1436.

2. Zezheng Liu, Kexuan Zhou, Kaiming Wang, Shijiao Guo, Hua Zhang. Thermosensitive bovine lactoferricin-loaded chitosan hydrogels for sustained antibacterial release: an alternative to antibiotics for treating bovine mastitis. Int J Biol Macromol,2025,303:140673.

3. Haoyi Shen , Yiran Zhao, Sizhe Zhang, Jiahui Xu,, Hua Yao, Hua Zhang. Synbiotic supplementation mitigates antibiotic-associated diarrhea by enhancing gut microbiota composition and intestinal barrier function in a canine model. Probiotics Antimicrob Proteins,2025,17(4):2586-2599.

4. Hua Zhang, Tianhang Lu, Shijiao Guo, Tianying He, Min-Kyoung Shin, Chaochao Luo, Jinjin Tong, Yinhua Zhang. Rumen microbes affect the somatic cell counts of dairy cows by modulating glutathione metabolismm. mSystems,2025,10(4):e0109324.

5. Shuang Gao, Liyun Tang, Jiayi Ma, Kaiming Wang, Hua Yao, Hua Zhang. Evaluation of the mechanism of Gong Ying San activity on dairy cows mastitis by network pharmacology and metabolomics analysis. PLoS One, 2024,19(4):e0299234.

6. Ruoxuan He, Shuang Gao, Hua Yao, Zixuan Zhao, Jinjin Tong, Hua Zhang. Mechanism of metabolic response to hepatectomy by integrated analysis of gut microbiota, metabolomics, and proteomics. Microbiol Spectr,2023,11(3):e0206722.

7. Hua Zhang, Ziyue Wang, Hua Yao, Linshu Jiang, Jinjin Tong. Intramammary infusion of matrine-chitosan hydrogels for treating subclinical bovine mastitis-effects on milk microbiome and metabolites. Front Microbiol,2022,13:950231.

8. Jinjin Tong, Defeng Cui, Hua Yao , Benhai Xiong, Lirong Cai, Hua Zhang, Linshu Jiang. A berberine hydrochloride-carboxymethyl chitosan hydrogel protects against Staphylococcus aureus infection in a rat mastitis model. Carbohydr Polym. 2022 15:278:118910.

V. Contact information

Postal address: College of Animal Science and Technology, Beijing University of Agriculture, No. 7, Beinong Road, Huilongguan, Changping, Beijing, 102206

Contact number: 010-80799141

Email: huazhang0914@126.com


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