Colleges & Faculties

Curriculum Vitae

Ⅰ. Personal information

Yan Wu, Ph.D., Professor, doctoral supervisor.

Member of the Standing Committee of the Party Committee and Vice President. Chief Scientist of Veterinary Medicine. PI of Laboratory of Animal Nutrition and Health, the College of Veterinary Medicine, Beijing University of Agriculture (BUA).

Prof. Wu is the recipient of New Century Excellent Talents in University of the Ministry of Education, Leading Talent of Beijing High-level Innovation Plan - Millions of Talents Project, Beijing BaiQianWan Talents, and Beijing Science and Technology New Star.

She concurrently serves as Adjunct Professor of Beijing Institute for Brain Disorders, Fellow of the Royal Society of Biology (FRSB), Director of Beijing Alzheimer's Prevention Association, and Director of Beijing Neuroscience Society; formerly served as Executive Director of the Medical Education Professional Committee of China Association of Higher Education, Expert for Clinical Medicine Certification of the Ministry of Education, Deputy Secretary-General of the Education Steering Committee for Clinical Medicine of the Ministry of Education, Inspector of the Education Supervision Committee of the Beijing Municipal People's Government, Vice President of Beijing Medical Education Association, Deputy Secretary-General of Beijing Anatomy Society, and Director of Beijing Cognitive Neuroscience Society.

Ⅱ. Research interests

Mechanism research of Alzheimer's Disease (AD); Research on food-derived natural extracts and chronic diseases, infectious diseases.

Ⅲ. Education and Work Experience

1. 2003. Graduated from The Chinese University of Hong Kong, Doctor of Medicine degree in Anatomy.

2. 2000. Graduated from Capital Medical University, Master of Medicine degree in Human Anatomy and Histology and Embryology.

3. 1997. Graduated from Capital Medical University, Bachelor of Medicine degree in Clinical Medicine.

Ⅳ. Courses

Animal Histology and Embryology; Homology of Medicine and Food and Health.

Ⅴ. Research Projects

She has presided over 15 national, provincial and ministerial projects, among which the most important are:

1. Municipal Education Commission - Municipal Natural Science Foundation Joint Funding Project (Key Project) "The influence and mechanism of hippocampal astrocyte AT1R on Aβ neuronal toxicity", Principal Investigator (2021-2023).

2. National Natural Science Foundation of China (General Program) "Mechanism of astrocyte NMDA receptors regulating NGF to affect Aβ hippocampal neuronal toxicity",  Principal Investigator (2018-2021).

3. Beijing Natural Science Foundation (General Program) "Mechanism research on dynamic influence of hippocampal astrocytes on caspase pathway-dependent Aβ neurotoxicity",  Principal Investigator (2015-2017).

Ⅵ. Major Achievements

She has published 131 research articles and won 5 awards, among which the most important are:

(I) Awards and Honors

1. Frontier Academic Achievements of the Capital (Beijing Association for Science and Technology, 2024).

2. Science and Technology Award of Capital Medical University, First Completion Person (2022).

3. Excellent Undergraduate Graduation Design (Thesis) of Beijing Colleges and Universities, Excellent Advisor (2022).

4. Excellent Undergraduate Teaching Administrator of Beijing Universities (2019).

5. Candidate for Beijing Municipal Millions of Talents Project (2015).

6. Beijing Young Top Talent (2013).

7. Outstanding Talents of the New Century, Ministry of Education (2010)

(II) Teaching Achievements

1. 3 times Second Prize of the Second National Textbook Construction Award (November 2025 announced).

2. Beijing Higher Education Quality Undergraduate Teaching Material and Courseware Award.

3. First Prize of China University Press Book Award for Excellent Teaching Materials.

4. Presided over 2 provincial and ministerial key and major educational reform projects.

5. Chief editor and deputy chief editor of 10 teaching books.

6. Published 43 educational reform papers.

(III) Representative Papers

1. Du X, Wang H, Liu S, Song Y, Chen X, Chen Z, Zhou R, Du J, Zhang W, Gao R, Li H, Zhang G, Mao X, Chang L, Wu Y. Astrocytic GluN2A alleviates sleep deprivation-induced elevation of Aβ through regulating neprilysin and AQP4 via the calcineurin/NFAT pathway. Prog Neurobiol. 2025 May;248:102744 (Corresponding author).

2. Liu S, Du X, Chen Z, Zhou R, Wang H, Mao X, Du J, Zhang G, Li H, Song Y, Chang L, Wu Y. Activation of astrocytic NMDA receptors counteracted Aβ-induced reduction of BDNF and elevation of GFAP and complement 3 in the hippocampal astrocytes. Neuroscience. 2024 Nov 1;559:303-315 (Corresponding author).

3. Guo W, Mao X, Han D, Wang H, Zhang W, Zhang G, Zhang N, Nie B, Li H, Song Y, Wu Y, Chang L. Sleep deprivation aggravated amyloid β oligomers-induced damage to the cerebellum of rats: Evidence from magnetic resonance imaging. Aging Brain. 2023 Aug 5;4:100091 (Corresponding author).

4. Chen X, Gao R, Song Y, Xu T, Jin L, Zhang W, Chen Z, Wang H, Wu W, Zhang S, Zhang G, Zhang N, Chang L, Liu H, Li H, Wu Y. Astrocytic AT1R deficiency ameliorates Aβ-induced cognitive deficits and synaptotoxicity through β-arrestin2 signaling. Prog Neurobiol. 2023 Sep;228:102489 (Corresponding author).

5. Zhang W, Chen X, Du Z, Mao X, Gao R, Chen Z, Wang H, Zhang G, Zhang N, Li H, Song Y, Chang L, Wu Y. Knockdown of astrocytic Grin2a/Grin2b ameliorates Aβ-induced synaptic toxicity and cognitive deficits. Neurobiol Aging. 2023 Oct;131:77-89 (Corresponding author).

Ⅶ. Contact information

Postal address: College of Animal Science and Technology, Beijing University of Agriculture, No. 7, Beinong Road, Huilongguan, Changping, Beijing, 102206

Contact number: +86-010-80799009

Email: yanwu@bua.edu.cn