Colleges & Faculties

CURRICULUM  VITAE

NAME:                               wenke ruan  

GENDER:                             Male

DATE OF BIRTH:                1978

PLACE OF BIRTH:            Shandong province, China

CITIZENSHIP:                    China

ADDRESS:           Office:

Department of Animal Science and Technology

Beijing University of Agriculture

Changping District, Huilongguan Beinong Road 7

Beijing , 102206

China

TELEPHONES:                   Office: ( 8610) - 80795593

                                                Fax:    (8610)80795593

E-MAIL:                                rwkmail@163.com; wenkeruan@hotmail.com

EDUCATION

ACADEMIC APPOINTMENT

2003- 2006    Assistant lecturer in the College of Animal Science and Technology of Beijing University of Agriculture.

2007-2012    Lecturer in the College of Animal Science and Technology of Beijing University of Agriculture.

2012-2024          Assistant Professor in the College of Animal Science and Technology of Beijing University of Agriculture.

2025- Professor in the College of Veterinary Medicine of Beijing University of Agriculture

PROFESSIONAL AND RESEARCH EXPERIENCE

2010-    :  Focus on animal microbiology and immunology. The current main research directions are the interaction between animal viral proteins and host proteins, as well as the interaction mechanism between immune molecules and pathogens.

2007-2010: As a doctoral research fellow in the avian toll like receptor and its polymorphism in different chicken breeds in China agriculture university (mentor: Shijun Zheng).

2003-2007: My research work focused on avian infectious bronchitis virus, and avian avian colibacillosis. I have begun to teaching animal microbiology and animal immunology in the College of Animal Science and Technology of Beijing University of Agriculture.

2000-2003: My reseach work focused on the avian influenza virus (AIV). We isolated AIV from chicken, duck, goose and quail, detected the pathogenicity to goose, and draw the phylogenetic tree of HA gene. (mentor: Guoqiang Zhu).

REPRESENTATIVE WORKS

1. The National Natural Science Foundation of China, 2016

2. The General Program of the Beijing Natural Science Foundation, 2012

3. The Vegetable Basket Program of the Beijing Municipal Commission of Agriculture, 2016

4. The Innovation Voucher Program of the Beijing Municipal Science and Technology Commission, 2019, 2020

5. The Scientific Research Plan Program of the Beijing Municipal Education Commission, 2013, 2019

6. The Golden Bridge Seed Program of the Beijing Association for Science and Technology. 2022

7. Cultivation Plan for Young Top-notch Talents in Beijing Municipal Colleges and Universities. 2015

8. Beijing Excellent Talent Cultivation Plan, 2007

PUBLICATIONS

1. Hao Dong, Yue Hao, Jue Wang, Shengkui Xu, Wenke Ruan. Japanese Encephalitis virus NS1 inhibits IFNβ production by 1 interacting with DDX3X, 2025, Journal of Virology. Corresponding author

2. Hao Dong, Xueyan Li, Shengkui Xu, Yuxin Wang, Ting Xia, Peng Li, Wenke Ruan. Proteomic analyses identify intracellular targets for avian coronavirus NSP10，Archives of Virology, 2025, 170:74. Corresponding author

3. Ting xia, Shengkui xu, Xueyan li, Wenke ruan. Avian coronavirus infectious bronchitis virus Beaudette Strain NSP9 interacts with STAT1 and inhibits its phosphorylation to facilitate viral replication. Virology, 2024 Feb:590:109944. Corresponding author

4. Hao Dong , Shengkui Xu , Peng Li , Wenke Ruan. The battle between infectious bronchitis virus and innate immunity: A mini review. Virology. 2024 Nov 29:603:110321. doi: 10.1016/j.virol.2024.110321. Corresponding author

5. Shengkui Xu, Bowen Zhang, Jielin Yao, Wenke Ruan. A new H9 influenza virus mRNA vaccine elicits robust protectiveimmunity against infection. Vaccine, Volume 41, Issue 18, 2 May 2023, Pages 2905-2913. Corresponding author

6. Li X, Li Q, Ruan W. Identification of Avian Toll-Like Receptor 3 and7 and Analysis of Gene Variation Sites. Brazilian Journal of Poultry Science.2022, 24(3).

7. Peng Wang, Xinze Liu, Qi Li, Jue Wang, Wenke Ruan. Proteomic analyses identify intracellular targets for Japanese encephalitis virus nonstructural protein 1 (NS1). Virus Res, 2021 Jun 24;302:198495. doi: 10.1016/j.virusres.2021.198495. Corresponding author

8. Jinyan Zhu, Shuang Xu, Xueyan Li, Jue Wang, Yueqi Jiang, Weichen Hu, Wenke Ruan, Infectious Bronchitis Virus Inhibits Activation of the TLR7 Pathway, but Not the TLR3 Pathway. Arch Virol, 2020 Jun 10;1-7.doi:10.1007/s00705-020-04690-8.  Corresponding author

9. Peng Wang, Jinyan Zhu, Xinze Liu, Jiaojiao Guo, Xuejia Gu, Wenke Ruan. Isolation and recombinant analysis of variants of porcine epidemic diarrhea virus strains from Beijing, China. VirusDis. DOI 10.1007/s13337-019-00513-w1, 2019. Corresponding author

10. Wenke Ruan，Jian An，YanhuaWu, Polymorphisms of chicken TLR3 and 7 in different breeds, PLoS ONE 2015.10(3): e0119967. doi:10.1371/journal. pone.0119967. Corresponding author

11. JJ Zhang, LX Wang, WK Ruan, J An. Investigation into the prevalence of coccidiosis and maduramycin drug resistance in chickens in China. Veterinary Parasitology，2013 Jan 16;191(1-2):29-34.   co-First Author

12. WK Ruan, YH Wu, J An, SJ Zheng. Polymorphisms of chicken Toll-like receptors 4, 15, and 21 in different breeds. Poultry Science, 91, 2512-2516, 2012. Corresponding author

13. Yanhua Wu, Wenke Ruan, Defeng Cui, Huanrong li. Identification of a toll-like receptor1 in guinea fowl (Agelastesniger). Biochemical genetics, 50, 702–716, 2012. Corresponding author

14. WK Ruan, YH Wu, J An, DF Cui, HR Li, SJ Zheng. Toll-like receptor 2 type 1 and type 2 polymorphisms in different chicken breeds. Poultry Science, 91, 101-106. 2012. First Author.

15. Wenke Ruan, Yanhua Wu, Shijun Zheng. Different genetic patterns in avian Toll-like receptor (TLR)5 genes. Molecular Biology Reports, 39, 3419-3426, 2012, First Author.

WK Ruan and SJ Zheng. Polymorphisms of chicken toll-like receptor 1 type 1 and type 2 in different breeds. Poultry Science, 90, 1941-1947, 2011. First Author.